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ACHE Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P22303
Clone Names 80305110
Peptide ID 80305110
Additional Information
Gene ID 43
Other Names Acetylcholinesterase, AChE, ACHE
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7853b was selected from the C-term region of human ACHE. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.
Cellular Location Cell junction, synapse Secreted. Cell membrane; Peripheral membrane protein Isoform H: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side
Tissue Location Isoform H is highly expressed in erythrocytes.
Research Areas
Citations (0)

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Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. The Protein is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.


Liang,D., FEBS J. 276 (1), 94-108 (2009)Scacchi,R., Am. J. Med. Genet. B Neuropsychiatr. Genet. (2008)

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$ 80.00
Cat# BP7853b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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