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MEK2 (MAP2K2) Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P36507
Clone Names 3032111
Peptide ID 3032111
Additional Information
Gene ID 5605
Other Names Dual specificity mitogen-activated protein kinase kinase 2, MAP kinase kinase 2, MAPKK 2, ERK activator kinase 2, MAPK/ERK kinase 2, MEK 2, MAP2K2, MEK2, MKK2, PRKMK2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7961a was selected from the N-term region of human MAP2K2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAP2K2
Synonyms MEK2, MKK2, PRKMK2
Function Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity).
Research Areas
Citations (0)

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MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.


Burroughs, K.D., et al., Mol. Cancer Res. 1(4):312-322 (2003).Tran, H., et al., Mol. Cell. Biol. 23(20):7177-7188 (2003).Li, S.P., et al., Cancer Res. 63(13):3473-3477 (2003).Li, Y., et al., J. Biol. Chem. 278(16):13663-13671 (2003).Liu, X., et al., J. Biol. Chem. 277(42):39312-39319 (2002).

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$ 80.00
Cat# BP7961a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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