|Other Names||Probable leucine--tRNA ligase, mitochondrial, Leucyl-tRNA synthetase, LeuRS, LARS2, KIAA0028|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7980a was selected from the N-term region of human LARS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Mitochondrion matrix.|
|Tissue Location||Ubiquitously expressed, but highest expression in tissues with high metabolic rates, such as skeletal muscle, heart, and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
LARS2 is a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid.
Park,H., RNA 14 (11), 2407-2416 (2008)'t Hart,L.M., Diabetes 54 (6), 1892-1895 (2005)Sohm,B., J. Mol. Biol. 339 (1), 17-29 (2004)Yao,Y.N., Protein Expr. Purif. 30 (1), 112-116 (2003)
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