LARS2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q15031 |
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Clone Names | 71228125 |
Gene ID | 23395 |
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Other Names | Probable leucine--tRNA ligase, mitochondrial, Leucyl-tRNA synthetase, LeuRS, LARS2, KIAA0028 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7980a was selected from the N-term region of human LARS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | LARS2 (HGNC:17095) |
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Synonyms | KIAA0028 |
Function | Catalyzes the attachment of leucine to its cognate tRNA. |
Cellular Location | Mitochondrion matrix. |
Tissue Location | Ubiquitously expressed, but highest expression in tissues with high metabolic rates, such as skeletal muscle, heart, and kidney. |
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Provided below are standard protocols that you may find useful for product applications.
Background
LARS2 is a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid.
References
Park,H., RNA 14 (11), 2407-2416 (2008)'t Hart,L.M., Diabetes 54 (6), 1892-1895 (2005)Sohm,B., J. Mol. Biol. 339 (1), 17-29 (2004)Yao,Y.N., Protein Expr. Purif. 30 (1), 112-116 (2003)
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