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PI5K Blocking Peptide (Center)

Synthetic peptide

Product Information
Primary Accession Q9Y2I7
Additional Information
Gene ID 200576
Other Names 1-phosphatidylinositol 3-phosphate 5-kinase, Phosphatidylinositol 3-phosphate 5-kinase, FYVE finger-containing phosphoinositide kinase, PIKfyve, Phosphatidylinositol 3-phosphate 5-kinase type III, PIPkin-III, Type III PIP kinase, PIKFYVE, KIAA0981, PIP5K3
Target/Specificity The synthetic peptide sequence is selected from aa 937~948 of HUMAN PIKFYVE
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA0981, PIP5K3
Function The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo- inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.
Cellular Location Endosome membrane Note=Mainly associated with membranes of the late endocytic pathway
Research Areas
Citations (0)

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PIP5K3 belongs to a large family of lipid kinases that alter the phosphorylation status of intracellular phosphatidylinositol. Signaling by phosphorylated species of phosphatidylinositol regulates diverse cellular processes, including membrane trafficking and cytoskeletal reorganization.


Am. J. Hum. Genet. 77 (1), 54-63 (2005)
J. Biol. Chem. 278 (51), 50863-50871 (2003)
Mol. Biol. Cell 14 (11), 4581-4591 (2003)
J. Biol. Chem. 277 (49), 47276-47284 (2002)
Mol. Cell. Biol. 19 (1), 623-634 (1999)

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$ 80.00
Cat# BP8036c
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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