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PTPrho Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O14522
Clone Names 1121703
Additional Information
Gene ID 11122
Other Names Receptor-type tyrosine-protein phosphatase T, R-PTP-T, Receptor-type tyrosine-protein phosphatase rho, RPTP-rho, PTPRT, KIAA0283
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8420a was selected from the N-term region of human PTPrho . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA0283
Function May be involved in both signal transduction and cellular adhesion in the CNS.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in colon, lung, heart and testis, as well as in fetal and adult brain. Not detected in muscle and peripheral blood leukocytes.
Research Areas
Citations (0)

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PTPrho is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system.


McAndrew, P.E., et al., J. Comp. Neurol. 391(4):444-455 (1998).Hillier, L.D., et al., Genome Res. 6(9):807-828 (1996).McAndrew, P.E., et al., Brain Res. Mol. Brain Res. 56 (1-2), 9-21 (1998).Besco, J.A., et al., BMC Genomics 2 (1), 1 (2001).

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$ 80.00
Cat# BP8420a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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