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R MKP3 Antibody Blocking peptide

     
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Product Information
Primary Accession Q64346
Additional Information
Gene ID 116663
Other Names Dual specificity protein phosphatase 6, 3.1.3.16, 3.1.3.48, Mitogen-activated protein kinase phosphatase 3, MAP kinase phosphatase 3, MKP-3, Dusp6, Mkp3
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Dusp6
Synonyms Mkp3
Function Inactivates MAP kinases. Has a specificity for the ERK family (PubMed:8626780). Implicated in muscle and neuronal differentiation (PubMed:8631996). Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia (By similarity). Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain (By similarity).
Cellular Location Cytoplasm.
Tissue Location Expressed in lung, heart, brain, and kidney, but not significantly in skeletal muscle or testis
Research Areas
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$ 277.78
Cat# BP8445a
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