|Other Names||Rho-related BTB domain-containing protein 3, 361-, RHOBTB3, KIAA0878|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8502b was selected from the C-term region of human RHOBTB3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Rab9-regulated ATPase required for endosome to Golgi transport. Involved in transport vesicle docking at the Golgi complex, possibly by participating in release M6PRBP1/TIP47 from vesicles to permit their efficient docking and fusion at the Golgi. Specifically binds Rab9, but not other Rab proteins. Has low intrinsic ATPase activity due to autoinhibition, which is relieved by Rab9.|
|Cellular Location||Golgi apparatus|
|Tissue Location||Ubiquitous. Highly expressed in neural and cardiac tissues, pancreas, placenta and testis|
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Provided below are standard protocols that you may find useful for product applications.
RHOBTB3 is a member of the evolutionarily conserved RHOBTB subfamily of Rho GTPases.
Wheeler,H.E., et.al., PLoS Genet. 5 (10), E1000685 (2009)
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