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TPT1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P13693 |
|---|---|
| Clone Names | 80924259 |
| Gene ID | 7178 |
|---|---|
| Other Names | Translationally-controlled tumor protein, TCTP, Fortilin, Histamine-releasing factor, HRF, p23, TPT1 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8505c was selected from the Center region of human TPT1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TPT1 |
|---|---|
| Function | Involved in calcium binding and microtubule stabilization (PubMed:12167714, PubMed:15162379, PubMed:15958728). Acts as a negative regulator of TSC22D1-mediated apoptosis, via interaction with and destabilization of TSC22D1 protein (PubMed:18325344). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
TPT1 is involved in calcium binding and microtubule stabilization.
References
Choi,S., et.al., PLoS ONE 4 (6), E5732 (2009)Sanchez,J.C., et.al., Electrophoresis 18 (1), 150-155 (1997)
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