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NR1H2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P55055
Clone Names 90625148
Peptide ID 90625148
Additional Information
Gene ID 7376
Other Names Oxysterols receptor LXR-beta, Liver X receptor beta, Nuclear receptor NER, Nuclear receptor subfamily 1 group H member 2, Ubiquitously-expressed nuclear receptor, NR1H2, LXRB, NER, UNR
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8526a was selected from the N-term region of human NR1H2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NR1H2
Synonyms LXRB, NER, UNR
Function Nuclear receptor. Binds preferentially to double- stranded oligonucleotide direct repeats having the consensus half- site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407}
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation.


Petruzzelli,M.,, FEBS Lett. 583 (8), 1274-1280 (2009)Dahlman,I.,, BMC Med. Genet. 10, 27 (2009)

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$ 80.00
Cat# BP8526a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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