|Other Names||Long-chain specific acyl-CoA dehydrogenase, mitochondrial, LCAD, ACADL|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8536c was selected from the Center region of human ACADL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Mitochondrion matrix.|
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Provided below are standard protocols that you may find useful for product applications.
ACADL belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid.
Lu,Y., et.al., J. Lipid Res. 49 (12), 2582-2589 (2008)Lea,W., et.al., Biochim. Biophys. Acta 1485 (2-3), 121-128 (2000)
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