|Other Names||Heat shock 70 kDa protein 13, Microsomal stress-70 protein ATPase core, Stress-70 protein chaperone microsome-associated 60 kDa protein, HSPA13, STCH|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8570a was selected from the N-term region of human STCH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Has peptide-independent ATPase activity.|
|Cellular Location||Microsome. Endoplasmic reticulum.|
|Tissue Location||Constitutively expressed in all tissues.|
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Provided below are standard protocols that you may find useful for product applications.
STCH is a member of the heat shock protein 70 family and is found associated with microsomes. Members of this protein family play a role in the processing of cytosolic and secretory proteins, as well as in the removal of denatured or incorrectly-folded proteins. This protein contains an ATPase domain and has been shown to associate with a ubiquitin-like protein.
Wistow,G., et.al., Mol. Vis. 8, 205-220 (2002)Aoki,M., et.al., Biochem. Biophys. Res. Commun. 335 (2), 566-574 (2005)
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