|Other Names||Killer cell immunoglobulin-like receptor 2DS4, CD158 antigen-like family member I, MHC class I NK cell receptor, Natural killer-associated transcript 8, NKAT-8, P58 natural killer cell receptor clones CL-39/CL-17, p58 NK receptor CL-39/CL-17, CD158i, KIR2DS4, CD158I, KKA3, NKAT8|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8581c was selected from the Center region of human KIR2DS4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||CD158I, KKA3, NKAT8|
|Function||Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
KIR2DS4 is the receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.
Campbell,K.S., et.al., Eur. J. Immunol. 28 (2), 599-609 (1998)Bottino,C., et.al., Eur. J. Immunol. 26 (8), 1816-1824 (1996)
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