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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   LPIN2 Antibody (Center) Blocking Peptide   

LPIN2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q92539
Clone Names 90723211
Peptide ID 90723211
Additional Information
Gene ID 9663
Other Names Phosphatidate phosphatase LPIN2, Lipin-2, LPIN2, KIAA0249
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8583c was selected from the Center region of human LPIN2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LPIN2
Synonyms KIAA0249
Function Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism (By similarity).
Cellular Location Nucleus. Cytoplasm, cytosol. Endoplasmic reticulum membrane Note=Translocates to endoplasmic reticulum membrane with increasing levels of oleate.
Tissue Location Expressed in liver, lung, kidney, placenta, spleen, thymus, lymph node, prostate, testes, small intestine, and colon.
Research Areas
Citations (0)

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Defects in LPIN2 are the cause of Majeed syndrome. Majeed syndrome is an autosomal recessive disorder combining features of chronic recurrent multifocal osteomyelitis, congenital dyserythropoietic anemia and inflammatory dermatosis.


Olsen,J.V.,, Cell 127 (3), 635-648 (2006)Ferguson,P.J.,, J. Med. Genet. 42 (7), 551-557 (2005)

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$ 80.00
Cat# BP8583c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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