|Other Names||NKG2-C type II integral membrane protein, CD159 antigen-like family member C, NK cell receptor C, NKG2-C-activating NK receptor, CD159c, KLRC2, NKG2C|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8630a was selected from the N-term region of human KLRC2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
|Tissue Location||Natural killer cells.|
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Provided below are standard protocols that you may find useful for product applications.
KLRC2 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
Seo,J., et.al., Tissue Antigens 70 (4), 307-313 (2007)Park,K.S., et.al., Tissue Antigens 72 (4), 342-346 (2008)
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