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MLX Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UH92
Clone Names 90805065
Peptide ID 90805065
Additional Information
Gene ID 6945
Other Names Max-like protein X, Class D basic helix-loop-helix protein 13, bHLHd13, Max-like bHLHZip protein, Protein BigMax, Transcription factor-like protein 4, MLX, BHLHD13, TCFL4
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8638c was selected from the Center region of human MLX. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MLX
Synonyms BHLHD13, TCFL4
Function Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
Cellular Location Isoform Alpha: Cytoplasm. Note=Found predominantly in the cytoplasm Isoform Gamma: Nucleus. Note=Found predominantly in the nucleus
Tissue Location Expressed in all tissues tested, including spleen, thymus, prostate, ovary, intestine, colon, peripheral blood leukocyte, heart, liver, skeletal muscle and kidney. Lower levels of expression in testis, brain, placenta and lung
Research Areas
Citations (0)

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MLX belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This protein may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4.


Meroni,G.,, Oncogene 19 (29), 3266-3277 (2000)Billin,A.N.,, J. Biol. Chem. 274 (51), 36344-36350 (1999)

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$ 80.00
Cat# BP8638c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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