DPPA2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q7Z7J5 |
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Clone Names | 70305168 |
Gene ID | 151871 |
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Other Names | Developmental pluripotency-associated protein 2, Pluripotent embryonic stem cell-related gene 1 protein, DPPA2, PESCRG1 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8642d was selected from the N-term region of human DPPA2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DPPA2 |
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Synonyms | PESCRG1 |
Function | Binds to target gene promoters, including NKX2-5 and SYCE1, but not GATA4, and may be involved in the maintenance of the active epigenetic status of these genes. |
Cellular Location | Nucleus. |
Tissue Location | Expressed in embryonic stem cells. No expression is seen in 5 months embryo, mesenchymal stem cells, embryonic fibrocytes and adult tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
DPPA2 may play a role in maintaining cell pluripotentiality.
References
John,T., et.al., Clin. Cancer Res. 14 (11), 3291-3298 (2008)Monk,M., et.al., Mol. Hum. Reprod. 14 (6), 347-355 (2008)
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