|Other Names||Developmental pluripotency-associated protein 2, Pluripotent embryonic stem cell-related gene 1 protein, DPPA2, PESCRG1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8642d was selected from the N-term region of human DPPA2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds to target gene promoters, including NKX2-5 and SYCE1, but not GATA4, and may be involved in the maintenance of the active epigenetic status of these genes.|
|Tissue Location||Expressed in embryonic stem cells. No expression is seen in 5 months embryo, mesenchymal stem cells, embryonic fibrocytes and adult tissues|
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Provided below are standard protocols that you may find useful for product applications.
DPPA2 may play a role in maintaining cell pluripotentiality.
John,T., et.al., Clin. Cancer Res. 14 (11), 3291-3298 (2008)Monk,M., et.al., Mol. Hum. Reprod. 14 (6), 347-355 (2008)
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