|Other Names||Solute carrier family 23 member 2, Na(+)/L-ascorbic acid transporter 2, Nucleobase transporter-like 1 protein, Sodium-dependent vitamin C transporter 2, hSVCT2, Yolk sac permease-like molecule 2, SLC23A2, KIAA0238, NBTL1, SLC23A1, SVCT2, YSPL2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8652a was selected from the N-term region of human SLC23A2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA0238, NBTL1, SLC23A1, SVCT2, YSPL2|
|Function||Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. TSLC23A2 accounts for tissue-specific uptake of vitamin C.
Hogue,D.L. ,et.al., Genomics 59 (1), 18-23 (1999)
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