SLC23A2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9UGH3 |
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Clone Names | 80917081 |
Gene ID | 9962 |
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Other Names | Solute carrier family 23 member 2, Na(+)/L-ascorbic acid transporter 2, Nucleobase transporter-like 1 protein, Sodium-dependent vitamin C transporter 2, hSVCT2, Yolk sac permease-like molecule 2, SLC23A2, KIAA0238, NBTL1, SLC23A1, SVCT2, YSPL2 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8652a was selected from the N-term region of human SLC23A2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SLC23A2 |
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Function | Sodium/ascorbate cotransporter (PubMed:10471399, PubMed:10556521). Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate (PubMed:10471399). |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Ubiquitous.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. TSLC23A2 accounts for tissue-specific uptake of vitamin C.
References
Hogue,D.L. ,et.al., Genomics 59 (1), 18-23 (1999)
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