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ICAM1 Antibody (C-term) Blocking PeptideSynthetic peptide
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| BP8656b | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ICAM1 Antibody (C-term) Blocking Peptide - Product info | |
| Primary Accession | P05362 |
| Clone Names | 81110092 |
| Calculated MW | 57825 Da |
ICAM1 Antibody (C-term) Blocking Peptide - Additional info | |
| Gene ID 3383 | |
| Target/Specificity The synthetic peptide sequence used to generate the antibody AP8656b was selected from the C-term region of human ICAM1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. | |
| Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
ICAM1 Antibody (C-term) Blocking Peptide - Protein Information | |
| Name ICAM1 | |
| Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation In case of rhinovirus infection acts as a cellular receptor for the virus | |
| Cellular Location Membrane; Single-pass type I membrane protein | |
ICAM1 Antibody (C-term) Blocking Peptide - Related products
AP2877b: CD54 Antibody (C-term)
AP8656b: ICAM1 Antibody (C-term)
RI12626: ICAM1 predesign siRNA
BP2877b: CD54 Antibody (C-term) Blocking Peptide
BP8656b: ICAM1 Antibody (C-term) Blocking Peptide
ICAM1 Antibody (C-term) Blocking Peptide - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
ICAM1 is a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.
REFERENCES
Denkers,I.A., et.al., Leuk. Res. 16 (5), 469-474 (1992)Rossler,K., et.al., J. Neurosci. Res. 31 (2), 365-374 (1992)
