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KIR3DS1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q14943 |
|---|---|
| Clone Names | 90713120 |
| Gene ID | 3813 |
|---|---|
| Other Names | Killer cell immunoglobulin-like receptor 3DS1, MHC class I NK cell receptor, Natural killer-associated transcript 10, NKAT-10, KIR3DS1, NKAT10 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8673b was selected from the C-term region of human KIR3DS1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | KIR3DS1 (HGNC:6340) |
|---|---|
| Synonyms | NKAT10 |
| Function | Receptor on natural killer (NK) cells for MHC class I molecules. Upon interaction with peptide-free HLA-F open conformer, triggers NK cell degranulation and anti-viral cytokine production. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in NK and T-cell lines but not in B- lymphoblastoid cell lines or in a colon carcinoma cell line |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KIR3DS1 is the receptor on natural killer (NK) cells for HLA-C alleles. It does not inhibit the activity of NK cells.
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