|Other Names||Solute carrier family 22 member 11, Organic anion transporter 4, SLC22A11, OAT4|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8679c was selected from the Center region of human SLC22A11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Detected in placenta and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
SLC22A11 is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. This protein is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus.
Babu,E., et.al., Jpn. J. Pharmacol. 88 (1), 69-76 (2002)
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