|Other Names||2-hydroxyacyl-CoA lyase 1, 41--, 2-hydroxyphytanoyl-CoA lyase, 2-HPCL, Phytanoyl-CoA 2-hydroxylase 2, HACL1, HPCL, HPCL2, PHYH2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8711b was selected from the C-term region of human PHYH2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||HPCL, HPCL2, PHYH2|
|Function||Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde.|
|Tissue Location||Expressed in high levels in liver, also expressed in kidney, heart and skeletal muscle|
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Provided below are standard protocols that you may find useful for product applications.
PHYH2 catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde.
Kikuchi,M., et.al., J. Biol. Chem. 279 (1), 421-428 (2004)
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