|Other Names||Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase, DERA|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8764a was selected from the N-term region of human DERA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation.|
|Cellular Location||Cytoplasm. Cytoplasmic granule. Nucleus. Note=Recruited to stress granules but not to processing bodies upon arsenite or clotrimazole treatment or energy deprivation.|
|Tissue Location||Mainly expressed in liver, lung and colon.|
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Provided below are standard protocols that you may find useful for product applications.
Sgarrella,F., et.al., Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 117 (2), 253-257(1997)
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