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CYP51A1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q16850
Clone Names 80311148
Peptide ID 80311148
Additional Information
Gene ID 1595
Other Names Lanosterol 14-alpha demethylase, LDM, CYPLI, Cytochrome P450 51A1, Cytochrome P450-14DM, Cytochrome P45014DM, Cytochrome P450LI, Sterol 14-alpha demethylase, CYP51A1, CYP51
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8874b was selected from the C-term region of human CYP51A1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYP51A1
Synonyms CYP51
Function Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
Cellular Location Endoplasmic reticulum membrane. Microsome membrane
Tissue Location Ubiquitously expressed with highest levels in testis, ovary, adrenal, prostate, liver, kidney and lung
Research Areas
Citations (0)

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CYP51A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol.


Wang,Y.,, J. Biol. Chem. 283 (39), 26332-26339 (2008)

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$ 80.00
Cat# BP8874b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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