|Other Names||3-beta-hydroxysteroid-Delta(8), Delta(7)-isomerase, Cholestenol Delta-isomerase, Delta(8)-Delta(7) sterol isomerase, D8-D7 sterol isomerase, Emopamil-binding protein, EBP|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9004a was selected from the N-term region of human EBP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus envelope Cytoplasmic vesicle. Note=During interphase, detected on the endoplasmic reticulum and the nuclear envelope. During mitosis, detected on cytoplasmic vesicles|
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Provided below are standard protocols that you may find useful for product applications.
EBP catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers.
Rakheja,D., et.al., Pediatr. Dev. Pathol. 10 (2), 142-148 (2007)
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