|Other Names||Serine/threonine-protein kinase 40, SINK-homologous serine/threonine-protein kinase, Sugen kinase 495, SgK495, STK40, SGK495, SHIK|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9026b was selected from the region of human STK40. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be a negative regulator of NF-kappa-B and p53- mediated gene transcription.|
|Cellular Location||Nucleus. Cytoplasm|
|Tissue Location||Strongly expressed in heart, brain, placenta, lung, skeletal muscle, kidney, spleen, thymus, prostate, liver, pancreas, testis, ovary, small intestine, colon and peripheral blood leukocytes.|
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Provided below are standard protocols that you may find useful for product applications.
STK40 may be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
Greenman C., et.al., Nature 446:153-158(2007).
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