|Other Names||AMP deaminase 2, AMP deaminase isoform L, AMPD2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9118c was selected from the Center region of human AMPD2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle.|
|Tissue Location||Highly expressed in cerebellum. Three isoforms are present in mammals: AMP deaminase 1 is the predominant form in skeletal muscle; AMP deaminase 2 predominates in smooth muscle, non-muscle tissue, embryonic muscle and undifferentiated myoblasts; AMP deaminase 3 is found in erythrocytes|
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Provided below are standard protocols that you may find useful for product applications.
AMP deaminase plays a critical role in energy metabolism.
Haas,A.L. et.al., Biochem. Biophys. Res. Commun. 305 (2), 421-427 (2003)Mahnke-Zizelman,D.K., et.al., Biochim. Biophys. Acta 1308 (2), 122-132 (1996)
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