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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   PTGER3 Antibody (N-term) Blocking Peptide   

PTGER3 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P43115
Clone Names 90805093
Peptide ID 90805093
Additional Information
Gene ID 5733
Other Names Prostaglandin E2 receptor EP3 subtype, PGE receptor EP3 subtype, PGE2 receptor EP3 subtype, PGE2-R, Prostanoid EP3 receptor, PTGER3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9132a was selected from the N-term region of human PTGER3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels
Research Areas
Citations (0)

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PTGER3 is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli.


Schmid,A.,, Eur. J. Biochem. 228 (1), 23-30 (1995)An,S.,, Biochemistry 33 (48), 14496-14502 (1994)

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$ 80.00
Cat# BP9132a
(40 western blots)
Availability: In Stock
Bulk Size
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