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AIFM3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96NN9
Clone Names 90909011
Peptide ID 90909011
Additional Information
Gene ID 150209
Other Names Apoptosis-inducing factor 3, 1---, Apoptosis-inducing factor-like protein, AIFM3, AIFL
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9174b was selected from the C-term region of human AIFM3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AIFM3
Synonyms AIFL
Function Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
Cellular Location Mitochondrion. Note=Does not translocate to the nucleus upon induction of apoptosis
Tissue Location Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
Research Areas
Citations (0)

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This protein encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.


Vierimaa,O.,, J. Endocrinol. Invest. 32 (6), 512-518 (2009)Hahn,M.A.,, J. Endocrinol. 201 (3), 387-396 (2009)

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$ 80.00
Cat# BP9174b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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