|Other Names||Destrin, Actin-depolymerizing factor, ADF, DSTN, ACTDP, DSN|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9189c was selected from the Center region of human DSTN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers (G-actin). Acts in a pH- independent manner.|
|Tissue Location||Widely distributed in various tissues.|
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Provided below are standard protocols that you may find useful for product applications.
DSTN belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This protein encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin).
Estornes,Y., et.al., Int. J. Cancer 121 (10), 2162-2171 (2007)Mannherz,H.G., et.al., J. Mol. Biol. 366 (3), 745-755 (2007)
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