|Other Names||ATPase family AAA domain-containing protein 1, Thorase, ATAD1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9194b was selected from the C-term region of human ATAD1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA- stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent (By similarity).|
|Cellular Location||Peroxisome. Cell junction, synapse, postsynaptic cell membrane|
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Provided below are standard protocols that you may find useful for product applications.
Vasilescu,J., et.al., J. Proteome Res. 6 (1), 298-305 (2007)Olsen,J.V. et.al., Cell 127 (3), 635-648 (2006)
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