|Other Names||High affinity immunoglobulin gamma Fc receptor IB, IgG Fc receptor IB, Fc-gamma RIB, FcRIB, hFcgammaRIB, FCGR1B, IGFRB|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9197b was selected from the C-term region of human FCGR1B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. May function in the humoral immune response.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
FCGR1B may bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. This protein may function in the humoral immune response.
Thomas,G., et.al., Nat. Genet. 41 (5), 579-584 (2009)Kuwano,Y., et.al., Arch. Dermatol. Res. 298 (10), 493-498 (2007)
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