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MPP6 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NZW5 |
|---|---|
| Clone Names | 80522054 |
| Gene ID | 51678 |
|---|---|
| Other Names | MAGUK p55 subfamily member 6, Veli-associated MAGUK 1, VAM-1, MPP6, VAM1 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9201c was selected from the Center region of human MPP6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PALS2 (HGNC:18167) |
|---|---|
| Synonyms | MPP6, VAM1 |
| Cellular Location | Membrane; Peripheral membrane protein |
| Tissue Location | Abundant in testis, brain, and kidney with lower levels detectable in other tissues |
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Provided below are standard protocols that you may find useful for product applications.
Background
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily.
References
Scheel,A.K., et.al., Ann. Rheum. Dis. 65 (5), 595-600 (2006)Rush,J., et.al., Nat. Biotechnol. 23 (1), 94-101 (2005)Rush,J., et.al., Nat. Biotechnol. 23 (1), 94-101 (2005)
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