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SNF2L Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P28370
Clone Names 81201025
Additional Information
Gene ID 6594
Other Names Probable global transcription activator SNF2L1, 364-, ATP-dependent helicase SMARCA1, Nucleosome-remodeling factor subunit SNF2L, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1, SMARCA1, SNF2L, SNF2L1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9257b was selected from the C-term region of human SNF2L. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SMARCA1
Synonyms SNF2L, SNF2L1
Function [Isoform 1]: Catalytically inactive when either DNA or nucleosomes are the substrate and does not possess chromatin-remodeling activity (PubMed:15310751, PubMed:28801535). Acts as a negative regulator of chromatin remodelers by generating inactive complexes (PubMed:15310751).
Cellular Location Nucleus.
Tissue Location [Isoform 1]: Mainly expressed in non-neuronal tissues such as lung, breast, kidney, and ovary
Research Areas
Citations (0)
citation

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Background

SNF2L encodes a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes.

References

Ye,Y., et.al., Mol. Cancer Res. 7 (12), 1984-1999 (2009)Xia,Y., et.al., Biochem. Biophys. Res. Commun. 368 (2), 438-444 (2008)Lazzaro,M.A., et.al., BMC Med. Genet. 9, 11 (2008)

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$ 277.78
Cat# BP9257b
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