|Other Names||Complement component C7, C7|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9262c was selected from the Center region of human C7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor.|
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Provided below are standard protocols that you may find useful for product applications.
C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection.
Davila,S., et.al., Genes Immun. 11 (3), 232-238 (2010)Kuijpers,T.W., et.al., Mol. Immunol. 47 (4), 671-677 (2010)Wheeler,H.E., et.al., PLoS Genet. 5 (10), E1000685 (2009)
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