|Other Names||Neuropeptide Y receptor type 5, NPY5-R, NPY-Y5 receptor, NPYY5-R, Y5 receptor, NPY5R, NPYR5|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9265c was selected from the Center region of human NPY5R. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Brain; hypothalamus.|
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Provided below are standard protocols that you may find useful for product applications.
NPY5R is receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. NPY5R seems to be associated with food intake. This protein could be involved in feeding disorders.
Gratacos,M., et.al, Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009)Arnett,D.K., et.al, J. Hypertens. 27 (8), 1585-1593 (2009)Umeda,T., et.al, Peptides 30 (8), 1441-1447 (2009)
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