|Other Names||EGF-containing fibulin-like extracellular matrix protein 2, Fibulin-4, FIBL-4, Protein UPH1, EFEMP2, FBLN4|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9269b was selected from the C-term region of human EFEMP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
EFEMP2 have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein contains four EGF2 domains and six calcium-binding EGF2 domains. This protein is necessary for elastic fiber formation and connective tissue development.
Chen,Q., et.al. Biochem. J. 423 (1), 79-89 (2009)Choudhury,R., et.al, J. Biol. Chem. 284 (36), 24553-24567 (2009)El-Hallous,E., et.al, J. Biol. Chem. 282 (12), 8935-8946 (2007)
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