EFTUD2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q15029 |
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Clone Names | 90921170 |
Gene ID | 9343 |
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Other Names | 116 kDa U5 small nuclear ribonucleoprotein component, Elongation factor Tu GTP-binding domain-containing protein 2, SNU114 homolog, hSNU114, U5 snRNP-specific protein, 116 kDa, U5-116 kDa, EFTUD2, KIAA0031, SNRP116 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9288c was selected from the Center region of human EFTUD2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | EFTUD2 |
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Synonyms | KIAA0031, SNRP116 |
Function | Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (PubMed:28502770, PubMed:28781166, PubMed:28076346, PubMed:29361316, PubMed:30315277, PubMed:29360106, PubMed:29301961, PubMed:30705154, PubMed:25092792). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (PubMed:16723661). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). |
Cellular Location | Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
EFTUD2 is component of the U5 snRNP complex required for pre-mRNA splicing.
References
Miele,A., et.al, J. Cell. Biochem. 102 (1), 136-148 (2007)Koch,H.B., et.al, Cell Cycle 6 (2), 205-217 (2007)Ewing,R.M., et.al, Mol. Syst. Biol. 3, 89 (2007)
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