|Other Names||116 kDa U5 small nuclear ribonucleoprotein component, Elongation factor Tu GTP-binding domain-containing protein 2, SNU114 homolog, hSNU114, U5 snRNP-specific protein, 116 kDa, U5-116 kDa, EFTUD2, KIAA0031, SNRP116|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9288c was selected from the Center region of human EFTUD2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex required for pre-mRNA splicing. Binds GTP.|
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Provided below are standard protocols that you may find useful for product applications.
EFTUD2 is component of the U5 snRNP complex required for pre-mRNA splicing.
Miele,A., et.al, J. Cell. Biochem. 102 (1), 136-148 (2007)Koch,H.B., et.al, Cell Cycle 6 (2), 205-217 (2007)Ewing,R.M., et.al, Mol. Syst. Biol. 3, 89 (2007)
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