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ALG1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BT22 |
|---|
| Gene ID | 56052 |
|---|---|
| Other Names | Chitobiosyldiphosphodolichol beta-mannosyltransferase, Asparagine-linked glycosylation protein 1 homolog, Beta-1, 4-mannosyltransferase, GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase, GDP-mannose-dolichol diphosphochitobiose mannosyltransferase, Mannosyltransferase-1, MT-1, hMat-1, ALG1, HMAT1, HMT1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ALG1 (HGNC:18294) |
|---|---|
| Synonyms | HMAT1, HMT1 |
| Function | Catalyzes the addition of the first of nine mannose moieties to form a dolichol-lipid linked oligosaccharide intermediate required for proper N-linked glycosylation. |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass type II membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
The enzyme encoded by this protein catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. This protein is mutated in congenital disorder of glycosylation type Ik.
References
Grubenmann,C.E. Hum. Mol. Genet. 13 (5), 535-542 (2004)Kranz,C. Am. J. Hum. Genet. 74 (3), 545-551 (2004)Schwarz,M. Am. J. Hum. Genet. 74 (3), 472-481 (2004)
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