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C19orf46 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8N205
Peptide ID 90826136
Additional Information
Gene ID 163183
Other Names Nesprin-4, Nuclear envelope spectrin repeat protein 4, SYNE4, C19orf46
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SYNE4
Synonyms C19orf46
Function As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning (By similarity). Behaves as a kinesin cargo, providing a functional binding site for kinesin-1 at the nuclear envelope. Hence may contribute to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus (By similarity).
Cellular Location Nucleus outer membrane; Single-pass type IV membrane protein. Note=Localization at the nucleus outer membrane requires the presence of SUN1
Research Areas
Citations (0)

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C19orf46 contributes to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus.


Ota, T., et al. Nat. Genet. 36(1):40-45(2004)

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$ 80.00
Cat# BP9391c
(40 western blots)
Availability: In Stock
Bulk Size
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