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C19orf61 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9H0W8
Peptide ID 90826142
Additional Information
Gene ID 56006
Other Names Protein SMG9, Protein smg-9 homolog, SMG9, C19orf61
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SMG9
Synonyms C19orf61
Function Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8.
Research Areas
Citations (0)

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C19orf61 is component of the SMG1C complex, a mRNA surveillance complex that recognizes and degrades mRNAs containing premature translation termination codons (PTCs) via the nonsense-mediated mRNA decay (NMD). The complex probably acts by associating with ribosomes during tranlation termination on mRNPs. If an exon junction complex (EJC) is located 50-55 or more nucleotides downstream from the termination codon, SMG1 phosphorylates UPF1/RENT1, triggering nonsense-mediated mRNA decay (NMD). In the SMG1C complex, it is required for the efficient association between SMG1 and SMG8.


Yamashita, A., et al. Genes Dev. 23(9):1091-1105(2009)Olsen, J.V., et al. Cell 127(3):635-648(2006)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)

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$ 80.00
Cat# BP9392a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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