|Other Names||Pyridoxine-5'-phosphate oxidase, Pyridoxamine-phosphate oxidase, PNPO|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|
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Provided below are standard protocols that you may find useful for product applications.
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.
Musayev, F.N., et al. J. Biol. Chem. 284(45):30949-30956(2009)Khayat, M., et al. Mol. Genet. Metab. 94(4):431-434(2008)Song, H., et al. Schizophr. Res. 97 (1-3), 264-270 (2007) :Mills, P.B., et al. Hum. Mol. Genet. 14(8):1077-1086(2005)Kang, J.H., et al. Eur. J. Biochem. 271(12):2452-2461(2004)Musayev, F.N., et al. Protein Sci. 12(7):1455-1463(2003)
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