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PNPO Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NVS9 |
|---|
| Gene ID | 55163 |
|---|---|
| Other Names | Pyridoxine-5'-phosphate oxidase, Pyridoxamine-phosphate oxidase, PNPO |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PNPO |
|---|---|
| Function | Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). |
| Tissue Location | Ubiquitous. Expressed in liver, brain, lung, prostate and stomach (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.
References
Musayev, F.N., et al. J. Biol. Chem. 284(45):30949-30956(2009)Khayat, M., et al. Mol. Genet. Metab. 94(4):431-434(2008)Song, H., et al. Schizophr. Res. 97 (1-3), 264-270 (2007) :Mills, P.B., et al. Hum. Mol. Genet. 14(8):1077-1086(2005)Kang, J.H., et al. Eur. J. Biochem. 271(12):2452-2461(2004)Musayev, F.N., et al. Protein Sci. 12(7):1455-1463(2003)
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