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CCKBR Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P32239
Peptide ID 35313
Additional Information
Gene ID 887
Other Names Gastrin/cholecystokinin type B receptor, CCK-B receptor, CCK-BR, Cholecystokinin-2 receptor, CCK2-R, CCKBR, CCKRB
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CCKRB
Function Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Isoform 1 is expressed in brain, pancreas, stomach, the colon cancer cell line LoVo and the T-lymphoblastoma Jurkat, but not in heart, placenta, liver, lung, skeletal muscle, kidney or the stomach cancer cell line AGS. Expressed at high levels in the small cell lung cancer cell line NCI-H510, at lower levels in NCI-H345, NCI-H69 and GLC-28 cell lines, not expressed in GLC-19 cell line. Within the stomach, expressed at high levels in the mucosa of the gastric fundus and at low levels in the antrum and duodenum. Isoform 2 is present in pancreatic cancer cells and colorectal cancer cells, but not in normal pancreas or colonic mucosa. Isoform 3 is expressed in brain, pancreas, stomach, the stomach cancer cell line AGS and the colon cancer cell line LoVo.
Research Areas
Citations (0)

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CCKBR encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract.


Berg, N.D., et al. Int J Hyg Environ Health 213(2):131-139(2010)Chao, C., et al. Int. J. Cancer 126(4):864-875(2010)Tabakoff, B., et al. BMC Biol. 7, 70 (2009) Miyake, A. Biochem. Biophys. Res. Commun. 208(1):230-237(1995)Ito, M., et al. Cell Growth Differ. 5(10):1127-1135(1994)Herget, T., et al. Ann. N. Y. Acad. Sci. 713, 283-297 (1994)

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$ 80.00
Cat# BP9399a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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