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ELAC2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BQ52
Peptide ID 80317164
Additional Information
Gene ID 60528
Other Names Zinc phosphodiesterase ELAC protein 2, ElaC homolog protein 2, Heredity prostate cancer protein 2, Ribonuclease Z 2, RNase Z 2, tRNA 3 endonuclease 2, tRNase Z 2, ELAC2, HPC2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ELAC2
Synonyms HPC2
Function Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
Cellular Location Mitochondrion. Nucleus. Note=Mainly mitochondrial
Tissue Location Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes
Research Areas
Citations (0)

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ELAC2 has a C-terminal domain with tRNA; processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest.


Beuten, J., et al. Cancer Epidemiol. Biomarkers Prev. 19(2):588-599(2010)Elbarbary, R.A., et al. FEBS Lett. 583(19):3241-3246(2009)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Noda, D., et al. Oncogene 25(41):5591-5600(2006)Takaku, H., et al. Nucleic Acids Res. 31(9):2272-2278(2003)

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$ 80.00
Cat# BP9434c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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