|Other Names||CD177 antigen, Human neutrophil alloantigen 2a, HNA-2a, NB1 glycoprotein, NB1 GP, Polycythemia rubra vera protein 1, PRV-1, CD177, CD177, NB1, PRV1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor|
|Tissue Location||Highly expressed in normal bone marrow and weakly expressed in fetal liver. Expressed on neutrophils Expressed in granulocytes of patients with polycythemia vera (PV) and with essential thrombocythemia (ET)|
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Provided below are standard protocols that you may find useful for product applications.
NB1, a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia.
Melis, S., et al. Acta Clin Belg 64(5):429-433(2009)Hu, N., et al. Autoimmun Rev 8(6):510-514(2009)Korkmaz, B., et al. J. Biol. Chem. 283(51):35976-35982(2008)Han, T.H., et al. Korean J Lab Med 26(2):114-118(2006)Kissel, K., et al. Eur. J. Immunol. 31(5):1301-1309(2001)Temerinac, S., et al. Blood 95(8):2569-2576(2000)
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