|Other Names||Integral membrane protein DGCR2/IDD, DGCR2, IDD, KIAA0163|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Predominantly expressed in brain, heart, lung and fetal kidney. Low levels in liver and adult kidney|
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DGCR2 encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome.
Georgi, A., et al. Psychiatr. Genet. 19 (2), 104 (2009) Wang, P., et al. BMC Genomics 10, 518 (2009) Ishiguro, H., et al. Psychiatr. Genet. 18(5):255-256(2008)Pellikka, M., et al. J. Thromb. Thrombolysis 26(2):91-96(2008)Olsen, J.V., et al. Cell 127(3):635-648(2006)
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