|Other Names||BMP/retinoic acid-inducible neural-specific protein 3, DBCCR1-like protein 1, BRINP3, DBCCR1L, DBCCR1L1, FAM5C|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||DBCCR1L, DBCCR1L1, FAM5C|
|Function||Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition. Promotes pituitary gonadotrope cell proliferation, migration and invasion, when overexpressed. May play a role in cell pituitary tumor development.|
|Cellular Location||Secreted. Mitochondrion|
|Tissue Location||Strongly expressed in oral keratinocytes compared to the weak expression in tongue squamous cell carcinoma (SCC). Expressed in endothelial and aortic smooth muscle cells Overexpressed in gonadotropinomas compared to normal pituitarie tissues.|
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Provided below are standard protocols that you may find useful for product applications.
Kuroiwa, T., et al. Oncol. Rep. 22(5):1005-1011(2009)Connelly, J.J., et al. BMC Med. Genet. 9, 33 (2008) Shorts-Cary, L., et al. Endocrinology 148(3):967-975(2007)
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