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CNTN1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q12860
Peptide ID 90429080
Additional Information
Gene ID 1272
Other Names Contactin-1, Glycoprotein gp135, Neural cell surface protein F3, CNTN1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNTN1
Function Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity).
Cellular Location Isoform 1: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side
Tissue Location Strongly expressed in brain and in neuroblastoma and retinoblastoma cell lines. Lower levels of expression in lung, pancreas, kidney and skeletal muscle
Research Areas
Citations (0)

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CNTN1 is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system.


Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :Compton, A.G., et al. Am. J. Hum. Genet. 83(6):714-724(2008)Melzer, D., et al. PLoS Genet. 4 (5), E1000072 (2008)

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$ 80.00
Cat# BP9490c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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