NUCKS1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H1E3 |
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Other Accession | NP_073568 |
Gene ID | 64710 |
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Other Names | Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1, P1, NUCKS1, NUCKS |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | NUCKS1 {ECO:0000303|PubMed:26323318, ECO:0000312|HGNC:HGNC:29923} |
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Function | Chromatin-associated protein involved in DNA repair by promoting homologous recombination (HR) (PubMed:26323318). Binds double-stranded DNA (dsDNA) and secondary DNA structures, such as D- loop structures, but with less affinity than RAD51AP1 (PubMed:26323318). |
Cellular Location | Nucleus. Chromosome |
Tissue Location | Widely expressed, with highest levels in thyroid gland, prostate and uterus and in fetal liver, thymus and lung |
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Provided below are standard protocols that you may find useful for product applications.
References
Satake, W., et al. Nat. Genet. 41(12):1303-1307(2009) Simon-Sanchez, J., et al. Nat. Genet. 41(12):1308-1312(2009) Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009) Wisniewski, J.R., et al. Proteins 73(3):710-718(2008) Grundt, K., et al. Biochim. Biophys. Acta 1773(9):1398-1406(2007)
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