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ASH2L Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9UBL3
Peptide ID 90819166
Additional Information
Gene ID 9070
Other Names Set1/Ash2 histone methyltransferase complex subunit ASH2, ASH2-like protein, ASH2L, ASH2L1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ASH2L
Synonyms ASH2L1
Function Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed. Predominantly expressed in adult heart and testis and fetal lung and liver, with barely detectable expression in adult lung, liver, kidney, prostate, and peripheral leukocytes
Research Areas
Citations (0)

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Background

Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.

References

Pullirsch, D., et al. Development 137(6):935-943(2010)Magerl, C., et al. Hum. Pathol. 41(2):181-189(2010)Patel, A., et al. J. Biol. Chem. 284(36):24242-24256(2009)Garapaty, S., et al. J. Biol. Chem. 284(12):7542-7552(2009)Southall, S.M., et al. Mol. Cell 33(2):181-191(2009)

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$ 80.00
Cat# BP9648c
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