|Other Names||Gamma-glutamylcyclotransferase, Cytochrome c-releasing factor 21, GGCT, C7orf24, CRF21|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the formation of 5-oxoproline from gamma- glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis.|
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Provided below are standard protocols that you may find useful for product applications.
GGCT (EC 22.214.171.124) catalyzes the formation of 5-oxoproline (pyroglutamic acid) from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis.
Oakley, A.J., et al. J. Biol. Chem. 283(32):22031-22042(2008)Bae, E., et al. Proteins 70(2):588-591(2008)Masuda, Y., et al. Biochem. Biophys. Res. Commun. 346(2):454-460(2006)
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